Around the year 1600, from his native Sarzana, Domenico Fiasella moved to Genoa where he joined the atelier of Aurelio Lomi first, and then the one of Giovan Battista Paggi. Towards the end of the first decade of the seventeenth century, thanks to the protection of the Bishop of Sarzana Giovanni Battista Salvago, he moved to Rome where he remained until 1615. The stay in the papal capital would prove decisive for the Italian painter who completed his training by studying the works realised by Bolognese painters such as Carracci, Reni and Domenichino and those made by Caravaggio and his followers Orazio and Artemisia Gentileschi.
The painter was able to examine their works in the collection of Marquis Giustiniani, his patron during his Roman years.
In 1616, the artist was back in Sarzana and the following year in Genoa, where he established himself as one of the most successful painters and subsequently numerous commissions were entrusted by both public and private. The frescoes representing the Stories of Esther in the Doge's Palace Giacomo Lomellini at the Zecca are an example that can be dated 1620.